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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GPKOW
All Species:
5.45
Human Site:
T216
Identified Species:
12
UniProt:
Q92917
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q92917
NP_056513.2
476
52229
T216
L
T
E
A
Q
A
L
T
P
T
G
P
S
R
M
Chimpanzee
Pan troglodytes
XP_001141772
224
23867
Rhesus Macaque
Macaca mulatta
XP_001105674
498
55226
T238
L
S
E
A
Q
A
L
T
P
T
G
P
S
H
M
Dog
Lupus familis
XP_538033
484
53417
V216
L
N
E
V
Q
A
L
V
P
T
G
P
H
H
L
Cat
Felis silvestris
Mouse
Mus musculus
Q56A08
488
53813
A216
R
M
E
A
Q
D
L
A
S
V
G
S
H
H
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507594
502
55083
G260
G
V
T
G
Q
E
C
G
P
A
G
V
T
G
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU07
487
54677
E206
R
S
A
L
K
H
L
E
P
Q
K
P
R
K
P
Zebra Danio
Brachydanio rerio
Q90X38
506
57936
E228
R
S
A
I
K
D
L
E
P
G
V
P
K
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_623528
264
29888
T36
N
A
S
P
Q
I
I
T
K
E
P
E
Q
L
V
Nematode Worm
Caenorhab. elegans
Q21924
462
51694
K206
K
N
P
V
G
K
N
K
N
T
G
E
S
S
K
Sea Urchin
Strong. purpuratus
XP_780912
479
55253
V199
R
K
P
G
E
P
A
V
K
A
E
E
E
E
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
33.8
68.4
80.7
N.A.
74.3
N.A.
N.A.
43.4
N.A.
45.7
44
N.A.
N.A.
24.1
26.2
32.3
Protein Similarity:
100
38.4
73.4
88.6
N.A.
82.5
N.A.
N.A.
56.3
N.A.
61.5
59.2
N.A.
N.A.
39.7
47
53.4
P-Site Identity:
100
0
86.6
60
N.A.
33.3
N.A.
N.A.
20
N.A.
20
26.6
N.A.
N.A.
13.3
20
0
P-Site Similarity:
100
0
93.3
66.6
N.A.
33.3
N.A.
N.A.
26.6
N.A.
40
40
N.A.
N.A.
26.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
10
19
28
0
28
10
10
0
19
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
19
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
37
0
10
10
0
19
0
10
10
28
10
10
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
10
0
0
19
10
0
0
10
0
10
55
0
0
10
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
19
28
0
% H
% Ile:
0
0
0
10
0
10
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
19
10
0
10
19
0
10
0
10
10
19
% K
% Leu:
28
0
0
10
0
0
55
0
0
0
0
0
0
10
10
% L
% Met:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
19
% M
% Asn:
10
19
0
0
0
0
10
0
10
0
0
0
0
0
0
% N
% Pro:
0
0
19
10
0
10
0
0
55
0
10
46
0
0
37
% P
% Gln:
0
0
0
0
55
0
0
0
0
10
0
0
10
0
0
% Q
% Arg:
37
0
0
0
0
0
0
0
0
0
0
0
10
19
0
% R
% Ser:
0
28
10
0
0
0
0
0
10
0
0
10
28
10
0
% S
% Thr:
0
10
10
0
0
0
0
28
0
37
0
0
10
0
0
% T
% Val:
0
10
0
19
0
0
0
19
0
10
10
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _